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Table 1 General characteristics of the studied groups of women

From: The estrogen receptor 1 gene affects bone mineral density and osteoporosis treatment efficiency in Slovak postmenopausal women

Variable

Total

N = 343

HT study

N = 76

Raloxifene study

N = 64

Age (years)

62.40 ± 0.46

63.22 ± 1.00

65.30 ± 0.98

Body mass index (BMI)

27.60 ± 0.08

27.30 ± 0.18

27.64 ± 0.17

BMD-FN (T-score)

−1.79 ± 0.03

− 2.13 ± 0.04

−2.16 ± 0.06

BMD-FN (g/cm2)

0.65 ± 0.01

0.60 ± 0.01

0.60 ± 0.01

BMD-LS (T-score)

−2.37 ± 0.04

−2.87 ± 0.04

− 2.95 ± 0.05

BMD-LS (g/cm2)

0.73 ± 0.01

0.68 ± 0.01

0.67 ± 0.01

Bone isoenzyme of alkaline phosphatase (μkat/l)

0.56 ± 0.04

1.17 ± 0.11

0.68 ± 0.08

Osteocalcin (μg/l)

3.85 ± 0.05

3.92 ± 0.11

4.25 ± 0.13

BetaCrosslaps (ng/l)

709.65 ± 13.57

795.23 ± 24.21

876.86 ± 28.06

Serum calcium (mmol/l)

2.40 ± 0.01

2.39 ± 0.02

2.46 ± 0.03

Serum phosphate (mmol/l)

1.20 ± 0.01

1.19 ± 0.02

1.23 ± 0.03

  1. Data are presented as Mean ± SE (SE – standard error of the mean)
  2. BMD bone mineral density, HT hormone therapy (17ß estradiol/progesterone)