Table 1 Demographics (Mean ± SD) of Non-Hispanic White Subjects in SPIROMICS
From: Genome-wide association study of lung function and clinical implication in heavy smokers
Cases | Controls | P value | |||||
|---|---|---|---|---|---|---|---|
All | Current smokers | Former smokers | All | Current smokers | Former smokers | ||
n | 1086 | 325 | 761 | 559 | 210 | 349 | NA |
Age at enrollment, years | 66.2 ± 7.6 | 62.9 ± 8.1 | 67.7 ± 6.9 | 63.6 ± 9.0 | 58.0 ± 9.1 | 66.9 ± 7.0 | < 0.0001 |
Female, n (%) | 437 (40) | 137 (42) | 300 (39) | 294 (53) | 122 (58) | 172 (49) | < 0.0001 |
Body mass index | 27.4 ± 5.1 | 25.7 ± 4.9 | 28.1 ± 5.0 | 28.6 ± 5.0 | 27.5 ± 5.1 | 29.2 ± 4.8 | < 0.0001 |
Current smokers, n (%) | 325 (30) | 325 (100) | 0 (0) | 210 (38) | 210 (100) | 0 (0) | 0.0019 |
Pack-years of cigarette smoking | 55.0 ± 25.7 | 52.6 ± 24.7 | 56.0 ± 26.1 | 46.3 ± 27.3 | 45.3 ± 31.1 | 46.9 ± 24.8 | < 0.0001 |
Post-bronchodilator FEV1/FVC | 0.52 ± 0.13 | 0.55 ± 0.11 | 0.50 ± 0.13 | 0.77 ± 0.05 | 0.78 ± 0.05 | 0.77 ± 0.05 | < 0.0001 |
Post-bronchodilator FEV1, % predicted | 60.1 ± 22.5 | 63.6 ± 19.7 | 58.6 ± 23.5 | 94.4 ± 13.9 | 93.4 ± 13.2 | 95.0 ± 14.3 | < 0.0001 |