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Table 1 Distribution of COMT Val158Met, depression and cardiovascular disease (CVD), stratified by gender

From: Association of Catechol-O-methyltransferase (COMT Val158Met) with future risk of cardiovascular disease in depressed individuals - a Swedish population-based cohort study

  All (n = 3525) Men (n = 1495) Women (n = 2030)
n (%)
Depression 556 (15.8) 157 (10.5) 399 (19.7)
Cardiovascular disease 236 (6.7) 152 (10.2) 84 (4.1)
COMT Val 158 Meta
 Met/Met 1094 (31.0) 457 (30.6) 637 (31.4)
 Met/Val 1720 (48.0) 722 (48.3) 998 (49.2)
 Val/Val 711 (20.2) 316 (21.1) 395 (19.5)
  Median (25th, 75th percentile)
Age [years] 46 (34, 55) 47 (35, 55) 45 (33, 54)
BMI [kg/m2]b 24.5 (22.5, 26.9) 25.3 (23.4, 27.4) 23.8 (22.0, 26.5)
  1. aMet/Met (A/A), Met/Val (A/G), Val/Val (G/G)
  2. bBMI: Body mass index