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Table 1 Subjects’ characteristics according to the SST poly T repeat polymorphism genotype in the entire sample and according to gender

From: Association study between a polymorphic poly-T repeat sequence in the promoter of the somatostatin gene and metabolic syndrome

All subjects
Genotype
13/13 13/14 13/15 13/16 p p*
n 913 69 571 172   
 Gender M/W % 52.0/48.0 55.1/44.9 50.6/49.4 57.6/42.4 0.42  
 Age (years) 49.7 ± 11.8 47.4 ± 11.7 50.1 ± 12.2 50.3 ± 12.1 0.33  
 CT (mmol/l) 5.96 ± 1.60 6.01 ± 1.85 6.00 ± 1.68 6.33 ± 2.01a 0.07 0.06
 HDL-C (mmol/l) 1.20 ± 0.45 1.14 ± 0.41 1.20 ± 0.47 1.11 ± 0.44 0.07 0.17
 LDL(mmol/l) 3.66 ± 1.47 3.70 ± 1.33 3.59 ± 1.25 3.74 ± 1.62 0.63 0.71
 TG (mmol/l) a 1.80 ± 2.22 1.89 ± 2.26 1.90 ± 2.12 2.19 ± 3.11 a 0.007 0.01
 WG (cm) 90.1 ± 13.1 92.3 ± 13.5 90.6 ± 13.0 94.0 ± 13.6 ac 0.004 0.009
 BMI (kg/m2) 26.8 ± 4.5 28.0 ± 5.0 27.0 ± 4.5 28.0 ± 4.5 ac 0.002 0.003
 Glycaemia (mmol/l) a 5.58 ± 1.49 5.87 ± 1.75 5.67 ± 1.68 5.82 ± 1.56 0.06 0.05
 Systolic BP (mmHg) 124.9 ± 19.4 122.2 ± 15.9 128.5 ± 20.5 131.1 ± 22.5 ab 0.001 < 0.001
 Diastolic BP (mmHg) 78.4 ± 11.5 79.0 ± 10.9 79.2 ± 11.1 80.9 ± 11.4 a 0.05 0.08
 FFA (mmol/l) a 0.49 ± 0.25 0.45 ± 0.24 0.50 ± 0.33 0.53 ± 0.28 0.14 0.12
 Glycerol (mmol/l) a 0.07 ± 0.09 0.06 ± 0.03 0.07 ± 0.28 0.07 ± 0.06 0.52 0.28
Men
Genotype 13/13 13/14 13/15 13/16 p p**
n 475 38 289 99   
 Age (years) 49.4 ± 11.2 48.2 ± 11.2 48.8 ± 11.7 49.9 ± 11.4 0.74  
 CT (mmol/l) 5.93 ± 1.57 6.17 ± 1.43 5.98 ± 1.61 6.35 ± 2.14 0.12 0.106
 HDL-C (mmol/l) 1.04 ± 0.34 1.01 ± 0.33 1.02 ± 0.31 0.94 ± 0.28 a 0.036 0.034
 LDL(mmol/l) 3.73 ± 1.46 4.03 ± 1.50 3.73 ± 1.30 3.79 ± 1.71 0.67 0.68
 TG (mmol/l) a 1.90 ± 2.30 2.08 ± 2.29 2.00 ± 2.12 2.44 ± 3.61 a 0.009 0.008
 WG (cm) 96.3 ± 10.4 96.8 ± 11.4 96.1 ± 11.0 99.1 ± 11.5 0.09 0.10
 BMI (kg/m2) 27.4 ± 3.9 28.1 ± 4.2 27.4 ± 4.0 28.2 ± 4.1 0.23 0.22
 Glycaemia (mmol/l) a 5.77 ± 1.64 6.31 ± 2.12 5.74 ± 1.48 5.87 ± 1.31 0.11 0.09
 Systolic BP (mmHg) 125.6 ± 17.0 121.9 ± 17.9 127.3 ± 18.9 127.7 ± 18.5 0.17 0.19
 Diastolic BP (mmHg) 80.1 ± 11.1 79.2 ± 11.3 79.4 ± 10.4 80.6 ± 10.9 0.73 0.78
 FFA (mmol/l) a 0.43 ± 0.24 0.40 ± 0.24 0.46 ± 0.29 0.49 ± 0.27 0.07 0.17
 Glycerol (mmol/l) a 0.06 ± 0.07 0.06 ± 0.03 0.10 ± 0.38 0.07 ± 0.06 0.37 0.39
Women
Genotype 13/13 13/14 13/15 13/16 p p**
n 438 31 282 73   
 Age (years) 50.1 ± 12.4 46.5 ± 12.3 51.4 ± 12.7 50.9 ± 13.0 0.16  
 CT (mmol/l) 5.99 ± 1.63 5.82 ± 2.27 6.02 ± 1.76 6.31 ± 1.83 0.45 0.49
 HDL-C (mmol/l) 1.37 ± 0.48 1.31 ± 0.44 1.38 ± 0.53 1.34 ± 0.51 0.83 0.88
 LDL(mmol/l) 3.57 ± 1.48 3.30 ± 0.96 3.44 ± 1.17 3.67 ± 1.50 0.37 0.37
 TG (mmol/l) a 1.69 ± 2.11 1.68 ± 2.23 1.80 ± 2.12 1.88 ± 2.15 0.49 0.63
 WG (cm) 83.5 ± 12.6 86.7 ± 13.9 85.0 ± 12.4 87.0 ± 13.2 0.07 0.05
 BMI (kg/m2) 26.1 ± 4.9 27.9 ± 6.0 26.5 ± 4.8 27.7 ± 5.1 0.019 0.013
 Glycaemia (mmol/l) a 5.37 ± 1.28 5.34 ± 0.91 5.60 ± 1.87 5.74 ± 1.86 0.13 0.16
 Systolic BP (mmHg) 124.1 ± 21.7 122.6 ± 13.4 129.7 ± 22.0a 135.8 ± 26.5 a < 0.001 < 0.001
 Diastolic BP (mmHg) 76.5 ± 11.6 78.7 ± 10.5 78.9 ± 11.8 81.3 ± 12.2 a 0.003 0.003
 FFA (mmol/l) a 0.57 ± 0.26 0.53 ± 0.23 0.55 ± 0.36 0.60 ± 0.29 0.42 0.66
 Glycerol (mmol/l) a 0.09 ± 0.11 0.08 ± 0.03 0.08 ± 0.08 0.09 ± 0.05 0.28 0.13
  1. All data are mean ± Standard deviation
  2. Significantly different (p <  0.05) as compared to (a) 13/13; (b) to 13/14; (c) to 13/15
  3. Significant p-value are in bold
  4. CT cholesterol total, HDL-C high density lipoprotein-cholesterol, LDL-C light density lipoprotein-cholesterol, TG triglycerides, WG Waist girth, BP blood pressure, BMI body mass index, FFA free fatty acid
  5. *age and gender included as a covariates
  6. **age included as a covariate
  7. a= geometrical mean and p-value obtained after log10 transformation