Fig. 4

Transcriptional repression activity of WT and p.H311Y mutant FOXL2. a. Expression level of WT and p.H311Y mutant FOXL2. b. Transcriptional repression activity of WT and p.H311Y mutant FOXL2 as measured by luciferase assay in both HeLa and KGN cells. Luciferase vector driven by the StAR promoter was cotransfected with empty vector, WT or p.H311Y mutant FOXL2 plasmids, followed by luciferase activity measurement. *p < 0.05, **p < 0.01