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Table 3 Summary of odds ratios (95% CI) in the analysis of the relationship between VEGF gene polymorphisms in rs2010963 and coronary artery disease susceptibility

From: Association of genetic polymorphisms in vascular endothelial growth factor with susceptibility to coronary artery disease: a meta–analysis

Genetic Model Overall and Subgroups N Test of Association Test of Heterogeneity
  OR 95%CI P –value P Heterogeneity I2 (%)
  Overall 10 1.18 0.94,1.48 0.140 0.002 65%
  PB 3 1.31 0.77,2.25 0.320 0.020 74%
CC + GC vs. GG HB 7 1.13 0.88,1.44 0.340 0.010 62%
  Large sample size 4 1.11 0.77,1.58 0.580 0.009 74%
  Small sample size 6 1.25 0.92,1.68 0.150 0.030 60%
  Asians 6 1.22 0.93,1.59 0.140 0.010 67%
  Caucasians 4 1.09 0.68,1.76 0.720 0.010 72%
  Overall 10 1.45 1.03,2.05 0.030 0.000 74%
  PB 3 1.26 0.64,2.48 0.500 0.050 67%
CC vs. GG + GC HB 7 1.56 0.97,2.53 0.070 0.000 79%
  Large sample size 4 1.43 0.74,2.74 0.290 0.000 72%
  Small sample size 6 1.52 1.01,2.33 0.040 0.050 55%
  Asians 6 1.50 0.98,2.31 0.060 0.000 82%
  Caucasians 4 1.35 0.70,2.60 0.370 0.110 51%
  Overall 10 1.18 0.90,1.57 0.240 0.000 76%
  PB 3 1.32 0.88,1.98 0.180 0.130 51%
GC vs. GG HB 7 1.14 0.79,1.64 0.490 0.000 81%
  Large sample size 4 1.28 0.72,2.28 0.400 0.060 65%
  Small sample size 6 1.14 0.89,1.46 0.290 0.190 32%
  Asians 6 1.25 0.85,1.84 0.260 0.000 83%
  Caucasians 4 1.08 0.72,1.63 0.710 0.060 59%
  Overall 10 1.57 1.02,2.42 0.040 0.000 77%
  PB 3 1.47 0.60,3.63 0.400 0.020 74%
CC vs. GG HB 7 1.60 0.93,2.77 0.090 0.000 81%
  Large sample size 4 1.24 0.68,2.28 0.480 0.000 71%
  Small sample size 6 2.03 1.26,3.28 0.007 0.070 50%
  Asians 6 1.62 0.94,2.79 0.080 0.000 84%
  Caucasians 4 1.40 0.42,4.61 0.580 0.002 73%
  Overall 10 1.19 0.98,1.44 0.080 0.000 78%
  PB 3 1.15 0.77,1.73 0.500 0.006 81%
C vs. G HB 7 1.20 0.94,1.53 0.140 0.000 80%
  Large sample size 4 1.10 0.84,1.43 0.490 0.001 814%
  Small sample size 6 1.27 1.03,1.78 0.030 0.010 72%
  Asians 6 1.24 0.98,1.58 0.070 0.000 83%
  Caucasians 4 1.08 0.73,1.60 0.690 0.006 76%
  1. Abbreviations: N number of studies; OR odds ratio; CI confidence interval; HB hospital–based; PB population–based; P–Value, P value for association; P Heterogeneity, P value for heterogeneity