S. No. | GJB2 and GJB6 genotypes | HI Husband (n=58)* | Frequency % | HI Wife (n=60) | Frequency % | Total (n=118) | Combined Frequency (%) |
---|---|---|---|---|---|---|---|
I | GJB2-Biallelic & Triallelic | Â | Â | Â | Â | Â | Â |
1 | W24X/W24X | 13 | 22.41 | 13 | 21.67 | 26 | 22.03 |
2 | V153I/V153I | 1 | 1.72 | 2 | 3.33 | 3 | 2.54 |
3 | W77X/W77X | 1 | 1.72 | 1 | 1.67 | 2 | 1.7 |
4 | R127H/R127H | 1 | 1.72 | 1 | 1.67 | 2 | 1.7 |
5 | R127H/V153I | 1 | 1.72 | 1 | 1.67 | 2 | 1.7 |
6 | V27I/E114G | 1 | 1.72 | 1 | 1.67 | 2 | 1.7 |
7 | E42D/E42D | 0 | 0 | 1 | 1.67 | 1 | 0.85 |
8 | W77X/Q124X | 0 | 0 | 1 | 1.67 | 1 | 0.85 |
9 | W24X/I35S | 0 | 0 | 1 | 1.67 | 1 | 0.85 |
10 | Q124X/IVS1+1G>A | 0 | 0 | 1 | 1.67 | 1 | 0.85 |
11 | R75Q#/V153I | 0 | 0 | 1 | 1.67 | 1 | 0.85 |
12 | V37I/V153I | 1 | 1.72 | 0 | 0 | 1 | 0.85 |
13 | V153I/R165W | 0 | 0 | 1 | 1.67 | 1 | 0.85 |
14 | R184Q#/Q124X/IVS1+1G>A | 1 | 1.72 | 0 | 0 | 1 | 0.85 |
15 | W24X/T55T/R127H | 1 | 1.72 | 0 | 0 | 1 | 0.85 |
II | GJB2-Monoallelic | Â | Â | Â | Â | Â | Â |
1 | R127H/+ | 9 | 15.52 | 9 | 15 | 18 | 15.25 |
2 | W24X/+ | 4 | 6.9 | 2 | 3.33 | 6 | 5.08 |
3 | V153I/+ | 2 | 3.45 | 1 | 1.67 | 3 | 2.54 |
4 | IVS1+1G>A/+ | 0 | Â | 2 | 1.67 | 2 | 1.7 |
5 | I35S/+ | 0 | Â | 1 | 1.67 | 1 | 0.85 |
III | GJB6-Monoallelic | Â | Â | Â | Â | Â | Â |
1 | R104H/+ | 1 | 1.72 | 0 | 0 | 1 | 0.85 |
2 | Q57R/+ | 1 | 1.72 | 0 | 0 | 1 | 0.85 |
IV | GJB2/GJB6-Digenic | Â | Â | Â | Â | Â | Â |
1 | E42D/+; R104H/+ | 1 | 1.72 | 0 | 0 | 1 | 0.85 |