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Table 5 Odds ratios (OR) of polymorphic rs5015480 HHEX genotypes for diabetesa in Korean men (n = 2887)

From: Effect of smoking on the association of HHEX (rs5015480) with diabetes among Korean women and heavy smoking men

   Normal Diabetesc
Subjects Genotype N (%) N (%) OR (95% CIb) P-value
Non smokers TT/TC 533(97.3) 68(97.1) 1.00 (reference)  
  CC 15(2.7) 2(2.9) 1.03(0.23–4.67) 0.9709
Ex smokers TT/TC 958(97.2) 113(99.1) 1.00 (reference)  
  CC 28(2.8) 1(0.9) 0.30(0.04–2.24) 0.2399
Light smokers TT/TC 409(94.0) 36(94.7) 1.00 (reference)  
(1–19/day) CC 26(6.0) 2(5.3) 0.83(0.19–3.69) 0.8040
Heavy smokers TT/TC 452(97.8) 50(92.6) 1.00 (reference)  
(≥20/day) CC 10(2.2) 4(7.4) 4.03(1.19–13.6) 0.0247
  1. aAdjusted for age
  2. bCI, confidence interval
  3. cDiabetes were defined as fasting serum glucose ≥126 mg/dL or medication
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BMC Medical Genetics

ISSN: 1471-2350

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