Table 3 IVDD-Control haplotype frequency comparison
Cytokine | Haplotype | IVDD | Control | P-Value | OR | 95% CI |
|---|---|---|---|---|---|---|
(N = 76) | (N = 140) | |||||
N (%) | N (%) | |||||
TGF-β (codon10,codon25) | CG | 65 (43) | 110 (39.9) | 0.54 | 1.14 | 0.75–1.71 |
TG | 73 (48.3) | 145 (52.5) | 0.42 | 0.85 | 0.57–1.26 | |
CC | 9 (6) | 21 (7.6) | 0.56 | 0.77 | 0.34–1.73 | |
TC | 3 (2) | 0 (0) | 0.04 | – | – | |
IL-10 (−1082,-819,-592) | GCC | 58 (38.2) | 99 (35.4) | 0.60 | 1.13 | 0.75–1.69 |
ACC | 19 (12.5) | 100 (35.7) | 0.000 | 0.26 | 0.15–0.44 | |
ATA | 62 (40.8) | 81 (28.9) | 0.014 | 1.69 | 1.12–2.56 | |
ACA | 10 (6.6) | 0 (0) | 0.000 | – | – | |
GCA | 1 (0.7) | 0 (0) | 0.35 | – | – | |
ATC | 2 (1.3) | 0 (0) | 0.12 | – | – |