Table 3 Genotype, allele and haplotype (rs1053004-rs1053005) frequencies of STAT3 rs1053004 and rs1053005 polymorphisms in hepatitis B virus infection resolvers and patients with chronic hepatitis
STAT3 polymorphism | Resolvers (n = 98) | CH (n = 239) | P | OR (95%CI) |
|---|---|---|---|---|
rs1053004 | ||||
Genotype | ||||
TT | 42 (42.9) | 108 (45.2) | Ref. | |
TC | 42 (42.9) | 103 (43.1) | 0.854 | 0.954 (0.575–1.581) |
CC | 14 (14.2) | 28 (11.7) | 0.501 | 1.286 (0.617–2.678) |
Allele | ||||
T | 126 (64.3) | 319 (66.7) | Ref. | |
C | 70 (35.7) | 159 (33.3) | 0.542 | 1.115 (0.786–1.580) |
rs1053005 | ||||
Genotype | ||||
AA | 44 (44.9) | 110 (46.0) | Ref. | |
AG | 41 (41.8) | 104 (43.5) | 0.814 | 0.946 (0.598–1.499) |
GG | 13 (13.3) | 25 (10.5) | 0.327 | 1.405 (0.711–2.777) |
Allele | ||||
A | 129 (65.8) | 324 (67.8) | Ref. | |
G | 67 (34.2) | 154 (32.2) | 0.396 | 1.149 (0.834–1.584) |
Haplotype | ||||
T-A | 126 (64.8) | 319 (66.7) | Ref. | |
C-G | 67 (34.2) | 154 (32.2) | 0.592 | 1.101 (0.774–1.568) |
T-G | 0 (0) | 0 (0) | 1.000 | 1.000 (1.000–1.000) |
C-A | 3 (1.0) | 5 (1.2) | 0.568 | 0.658 (0.155–2.796) |