MiR-146a G/C rs2910164 variation in South African Indian and Caucasian patients with psoriatic arthritis

BMC Medical Genetics

Table 2 Genotype and allele frequencies for all Indians and Caucasians (PsA patients + controls combined)

Frequency, n (%)	Indians (n = 146)^d	Caucasians (n = 70)^e	p value	RR (95% CI)	OR (95% CI)
Genotype, n (%)
GG	68 (46.57)	27 (38.57)	0.4536^a
GC	68 (46.57)	39 (55.71)
CC	10 (6.85)	4 (5.71)
GC + CC	78 (53.42)	43 (61.43)	0.3064^b	1.11 (0.92–1.33)	1.39 (0.78–2.48)
Allele, n (%)
G	204 (69.86)	93 (66.43)	0.5063^c	1.05 (0.91–1.22)	1.17 (0.76–1.08)
C	88 (30.14)	47 (33.57)	0.5063^c	1.05 (0.91–1.22)	1.17 (0.76–1.08)

CI confidence interval, DF degrees of freedom, RR relative risk, OR odds ratio, PsA psoriatic arthritis, χ² Chi-squared test
A p < 0.05 was considered as being significant
^aChi squared p value (Indians genotypes vs. Caucasians genotypes); χ² = 1.581, 2 DF. ^bFisher’s exact test p value (GG vs. GC + CC genotypes). ^cFisher’s exact test p value (Indians G and C alleles vs. Caucasians G and C alleles). ^dIndians (84 Indian PsA patients + 62 Indian controls). ^eCaucasians (32 Caucasian PsA patients + 38 Caucasian controls)

ISSN: 1471-2350