Table 5 Interaction analysis for rs660339 and hypertension and overweight on T2DM
rs660339 | Overweight | Hypertension | NGT | T2DM | P | OR |
|---|---|---|---|---|---|---|
GG/GA | No | No | 181 (45.5) | 93 (24.0) | Â | 1 |
GG/GA | No | Yes | 59 (14.8) | 77 (19.9) | <0.001 | 2.54 (1.67,3.87) |
GG/GA | Yes | No | 54 (13.6) | 77 (19.9) | <0.001 | 2.78 (1.81,4.26) |
GG/GA | Yes | Yes | 42 (10.6) | 76 (19.6) | <0.001 | 3.52 (2.24,5.54) |
AA | No | No | 33 (8.3) | 16 (4.1) | 0.861 | 0.94 (0.49,1.80) |
AA | No | Yes | 15 (3.8) | 7 (1.8) | 0.839 | 0.91 (0.36,2.31) |
AA | Yes | No | 9 (2.3) | 21 (5.4) | <0.001 | 4.54 (2.00,10.31) |
AA | Yes | Yes | 5 (1.3) | 20 (5.2) | <0.001 | 7.79 (2.83,21.40) |
Interaction of rs660339-overweight | Â | Â | Â | Â | 0.021 | Â |
Interaction of rs660339-hypertension | Â | Â | Â | Â | 0.441 | Â |
Interaction of rs660339-hypertension-overweight | Â | Â | Â | Â | 0.275 | Â |