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Table 4 Association analysis between rs6265 polymorphism and BDI scores in the first week following mTBI

From: The association between BDNF Val66Met polymorphism and emotional symptoms after mild traumatic brain injury

Genotype Sample no. (%) BDI scorea Codominant p value Dominant p value Recessive p value Log-additive p value
Total (n = 186)
 TT 41 (22.0) 12.56 ± 1.62 0.009** 0.144 0.002** 0.006**
 CT 89 (47.8) 8.83 ± 0.97     
 CC 56 (30.1) 7.06 ± 1.72     
Male (n = 60)
 TT 15 (25.0) 8.10 ± 1.22 0.093 0.050 0.107 0.029*
 CT 26 (43.3) 8.50 ± 2.09     
 CC 19 (31.7) 6.36 ± 3.15     
Female (n = 126)
 TT 26 (20.6) 15.18 ± 2.25 0.007** 0.381 0.002** 0.015*
 CT 63 (50.0) 8.95 ± 1.10     
 CC 37 (29.4) 7.43 ± 2.09     
  1. aMean ± standard error (s.e.). The p value was adjusted for GCS, GOSE, injury mechanism, antidepressant medication use and hypnotic medication use. *0.01 ≤ p < 0.05 is labeled in bold. **p < 0.01 is labeled in bold