Monoallelic characteristic-bearing heterozygous L1053X in BRCA2 gene among Sudanese women with breast cancer

BMC Medical Genetics

Table 3 The highly purified Breast Cancer Patients demographic, clinical, histological parameters with the nonsense mutation

Patients ID	Age	Family history of BC	grade	Stage and Metastasis	histotype	BC site	Nonsense Mutation
B1	51	second and third degree^*1	NA	T₁N₁M₀	NA	Rt/Unilateral
B2	45	No	NA	T_xN_xM_x	NA	Bilateral	Detected
B13^*2	27	No	III	T₂N₁M₀	Ductal	Lt/Unilateral
B14	35	Second degree	NA	T_xN_xM₁ (Liver)	Lobular	Rt/Unilateral	Detected
B18	41	No	II	T_xN_xM_x	Ductal	Rt/Unilateral
B23	27	No	NA	T₂N₀M₀	NA	Rt/Unilateral	Detected
B24	39	No	NA	T_xN_xM_x	NA	Rt/Unilateral	Detected
B29	37	No	III	T_xN_xM_x	Ductal	Rt/Unilateral
B39	30	No	II	T₄N₁M_x	Ductal	Lt/Unilateral
B44	57	No	I	T_xN_xM₁ (Bone/Lung)	Ductal	Rt/Unilateral

^*1Two of the relatives involved by breast cancer
^*2This patient was excluded from bioinformatics analysis due to inconsistency and poor quality

ISSN: 1471-2350