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Table 5 Comparative analysis of allele frequencies between the Kazakh population (present study) and other ethnic populations (HapMap data)

From: Association between 28 single nucleotide polymorphisms and type 2 diabetes mellitus in the Kazakh population: a case-control study

  Exact test of population differentiation (P value)
SNP ASW CEU CHB CHD GIH JPT LWK MEX MKK TSI YRI
rs3751812 0.26/0.11 (0.003) 0.26/0.46 (<10−5) 0.26/0.15 (0.01) 0.26/0.15 (0.009) 0.26/0.26 (1.000) 0.26/0.18 (0.1) 0.26/0.02 (<10−5) 0.26/0.17 (0.06) 0.26/0.13 (<10−5) 0.26/0.46 (<10−5) 0.26/0.07 (<10−5)
rs8050136 0.26/0.45 (<10−4) 0.26/0.46 (<10−5) 0.26/0.14 (0.002) .26/0.16 (0.02) 0.26/0.26 (1.000) 0.26/0.18 (0.08) 0.26/0.49 (<10−5) 0.26/0.20 (0.09) 0.26/0.48 (<10−5) 0.26/0.46 (<10−5) 0.26/0.46 (<10−5)
rs9939609 0.25/0.49 (<10−5) 0.25/0.46 (<10−5) 0.25/0.15 (0.01) .25/0.16 (0.03) 0.25/0.27 (0.8) 0.25/0.19 (0.2) 0.25/0.38 (<10−5) NA .25/0.47 (<10−5) 0.25/0.47 (<10−5) 0.25/0.49 (<10−5)
rs10811661 0.28/0.09 (<10−4) 0.28/0.20 (0.02) 0.28/0.42 (0.001) 0.28/0.44 (<10−3) 0.28/0.09 (<10−5) 0.28/0.48 (<10−5) 0.28/0.06 (<10−5) 0.28/0.11 (<10−3) 0.28/0.10 (<10−5) 0.28/0.19 (0.01) 0.28/0.02 (<10−5)
rs2383208 0.28/0.24 (0.5) 0.28/0.21 (0.09) .28/0.40 (0.004) 0.28/0.41 (0.001) 0.28/0.09 (<10−5) 0.28/0.45 (<10−4) 0.28/0.21 (0.2) 0.28/0.14 (0.01) .28/0.32 (0.2) 0.28/0.19 (0.02) 0.28/0.12 (<10−5)
rs1111875 0.41/0.23 (<10−5) 0.41/0.42 (<10−5) 0.41/0.32 (0.04) 0.41/0.31 (0.06) 0.41/0.41 (0.9) 0.41/0.35 (0.09) 0.41/0.19 (<10−5) 0.41/0.26 (<10−5) 0.41/0.24 (<10−5) 0.41/0.40 (<10−5) 0.41/0.13 (<10−5)
rs13266634 0.37/0.19 (<10−3) 0.37/0.24 (<10−3) 0 .37/0.47 (0.04) 0.37/0.44 (0.2) 0.37/0.23 (0.001) .37/0.44 (0.2) 0.37/0.06 (<10−5) 0.37/0.19 (0.002) 0.37/0.05(<10−5) 0.37/0.25 (0.006) 0.37/0.07(<10−5)
rs4506565 0.15/0.49 (<10−5) 0.15/0.30 (<10−5) 0.15/0.07 (0.01) 0.15/0.04 (<10−3) 0.15/0.30 (<10−5) 0.15/0.03 (<10−4) .15/0.49 (<10−5) 0.15/0.28 (0.005) 0.15/0.40 (<10−5) 0.15/0.39 (<10−5) 0.15/0.44 (<10−5)
rs5215 0 .34/0.19 (<10−5) .34/0.40 (0.09) 0.34/0.35 (0.7) 0.34/0.35 (0.8) 0.34/0.40 (0.2) 0.34/0.34 (1.0) 0.34/0.03 (<10−5) 0.34/0.42 (0.3) 0.34/0.06 (<10−5) 0.34/0.29 (0.4) 0.34/0.01 (<10−5)
rs7756992 0.33/0.46 (<10−5) 0.33/0.28 (0.2) 0.33/0.48 (<10−3) 0.33/0.49 (<10−5) 0.33/0.24 (0.07) 0.33/0.46 (0.001) 0.33/0.42 (<10−5) 0.33/0.34 (0.9) 0.33/0.41 (<10−5) 0.33/0.24 (0.02) 0.33/0.39 (<10−5)
rs4712523 0.32/0.40 (<10−5) 0.32/0.24 (0.8) 0.32/0.42 (0.02) 0.32/0.41 (0.02) 0.32/0.23 (0.04) 0.32/0.41 (0.04) 0.32/0.34 (<10−5) 0.32/0.31 (0.6) 0.32/0.46 (<10−5) 0.32/0.28 (0.1) 0.32/0.31 (<10−5)
rs9465871 0.30/0.46 (<10−5) 0.30/0.16 (<10−5) 0.30/0.50 (<10−5) 0.30/0.48 (<10−5) 0.30/0.22 (0.05) 0.30/0.44 (<10−5) 0.30/0.45 (<10−3) 0.30/0.32 (0.8) 0.30/0.46 (<10−5) 0.30/0.16 (<10−4) 0.30/0.39 (<10−5)
rs7961581 0.25/0.17 (0.2) 0.25/0.25 (0.4) 0.25/0.20 (0.06) 0.25/0.19 (0.05) 0.25/0.36 (0.003) 0.25/0.23 (0.9) 0.25/0.20 (0.3) 0.25/0.15 (0.06) 0.25/0.20 (0.3) 0.25/0.40 (<10−3) 0.25/0.17 (0.02)
rs864745 0.38/0.23 (0.01) 0.38/0.49 (0.001) 0.38/0.24 (0.002) 0.38/0.22 (<10−3) 0.38/0.22 (<10−3) 0.38/0.21 (<10−5) 0.38/0.20 (<10−5) 0.38/0.38 (0.6) 0.38/0.26 (<10−3) 0.38/0.49 (0.006) 0.38/0.23 (<10−4)
rs12779790 NA 0.17/0.23 (0.04) 0.17/0.13 (0.8) NA NA 0.17/0.12 (0.3) NA NA NA NA 0.17/0.05 (0.001)
rs10490072 0.13/0.15 (0.6) 0.13/0.27 (<10−5) 0.13/0.02 (<10−4) NA 0.13/0.15 (0.3) 0.13/0.01(<10−5) 0.13/0.04(0.001) 0.13/0.20(0.05) 0.13/0.02(<10−5) 0.13/0.21(0.009) 0.13/0.04 (0.001)
rs10923931 0.06/0.35 (<10−5) 0.06/0.09 (0.07) 0.06/0.02 (0.3) 0.06/0.02 (0.2) 0.06/0.21 (<10−5) 0.06/0.02 (0.2) 0.06/0.46 (<10−5) 0.06/0.09 (0.2) 0.06/0.36 (<10−5) 0.06/0.07 (0.2) 0.06/0.38 (<10−5)
rs7578597 0.06/0.27 (<10−5) 0.06/0.12 (<10−3) 0.06/0.14 (<10−5) 0.06/0.01 (0.008) 0.06/0.17 (<10−5) 0.06/0.01 (0.008) 0.06/0.36 (<10−5) 0.06/0.02 (0.3) 0.06/0.19 (<10−5) 0.06/0.06 (0.6) 0.06/0.33 (<10−5)
rs2025804 0.36/0.17 (<10−5) 0.36/0.38 (<10−5) 0.36/0.16 (<10−5) 0.36/0.11 (<10−5) 0.36/0.21 (<10−5) 0.36/0.15 (<10−5) 0.36/0.22 (<10−5) 0.36/0.35 (<10−5) 0.36/0.15 (<10−5) 0.36/0.27 (<10−5) 0.36/0.23 (<10−5)
rs2641348 0.05/0.35 (<10−5) 0.05/0.10 (0.01) 0.05/0.02 (0.09) 0.05/0.02 (0.08) 0.05/0.22 (<10−5) 0.05/0.02 (0.09) 0.05/0.46 (<10−5) 0.05/0.10 (0.06) 0.05/0.36 (<10−5) 0.05/0.08 (0.07) 0.05/0.38 (<10−5)
rs9472138 0.19/0.13 (0.2) 0.19/0.23 (0.2) 0.19/0.13 (0.07) NA 0.19/0.22 (0.4) 0.19/0.09 (0.001) 0.19/0.23 (0.3) 0.19/0.20 (0.4) NA 0.19/0.31 (<10−4) 0.19/0.15 (0.1)
rs1042714 NA 0.28/0.47 (<10−5) 0.28/0.12 (0.002) NA NA 0.28/0.08 (<10−3) NA NA NA NA 0.28/0.18 (0.03)
rs4994 0.17/0.08 (0.04) 0.17/0.09 (0.003) 0.17/0.11 (0.2) 0.17/0.14 (0.2) 0.17/0.11 (0.1) 0.17/0.19 (0.06) 0.17/ 0.09 (0.02) 0.17/ 0.09 (0.03) 0.17/0.13 (0.1) 0.17/0.04 (<10−5) 0.17/0.06 (<10−5)
rs1799883 0.35/0.22 (0.01) 0.35/0.33 (0.2) 0.35/0.32 (0.6) 0.35/0.21 (0.001) 0.35/0.36 (0.9) 0.35/0.32 (0.6) 0.35/0.19 (<10−5) 0.35/0.30 (0.6) 0.35/0.18 (<10−5) 035/0.25 (0.04) NA
rs1801282 0.14/0.02 (<10−3) 0.14/0.10(0.2 0.14/0.05 (0.001) 0.14/0.03 (<10−5) 0.14/ 0.09 (0.09) 0.14/0.03 (<10−4) NA 0.14/0.09 (0.5) 0.14/0.02 (<10−5) 0.14/0.07 (0.07) 0.14/0 (<10−5)
rs8192678 0.39/0.07 (<10−5) 0.39/0.35 (0.2) 0.39/0.40 (0.6) 0.39/0.40 (0.9) 0.39/0.30 (0.05) 0.39/0.47 (0.001) 0.39/0.02 (<10−5) 0.39/0.21 (<10−3) 0.39/0.08 (<10−5) 0.39/0.43 (0.5) 0.39/0.04 (<10−5)
rs780094 0.35/0.12 (<10−5) 0.35/0.41 (0.3) 0.35/0.41 (<10−5) NA 0.35/0.20 (<10−4) 0.35/0.42 (<10−5) 0.35/0.10 (<10−5) 0.35/0.34 (0.7) NA .35/0.50 (<10−4) 0.35/0.12 (<10−5)
rs7944584 0.13/0.06 (<10−5) 0.13/0.30 (<10−5) 0.13/0.05 (<10−5) NA 0.13/0.22 (<10−5) 0.13/0.02 (<10−5) 0.13/0 (<10−5) 0.13/0.19 (<10−5) NA 0.13/0.36 (<10−5) 0.13/0 (<10−5)
  1. Notes ASW: African ancestry living in the southwest USA
  2. CEU: Utah residents with Northern and Western European ancestry from the CEPH collection
  3. CHB: Han Chinese population in Beijing, China
  4. CHD: Chinese population in Metropolitan Denver, CO.
  5. GIH: Gujarati Indian population in Houston, TX
  6. JPT: Japanese population in Tokyo, Japan
  7. LWK: Luhya population in Webuye, Kenya. MEX: Mexicans in Los Angeles, CA. МKK: Maasai in Kinayawa, Kenya
  8. NA: Not availables
  9. TSI: Tuscan population in Italy
  10. YRI: Yoruban population in Ibadan, Nigeria
  11. NA: data not available from the HapMap
  12. The values represent the minor allele frequencies in Kazakh population/ in the other ethnicities (p value)