Table 4 Multivariable-adjusted hazard ratios by PEAR1 haplotypes
From: PEAR1 is not a major susceptibility gene for cardiovascular disease in a Flemish population
Haplotypes Event | N° of events (rate per 1000 person-years) | Hazard ratio (95% CI) | P | |
|---|---|---|---|---|
Carriers | Non carriers | |||
TTGATGGA (N° at risk) | 1174 | 764 |  |  |
 Total mortality | 146 (7.46) | 92 (7.37) | 1.05 (0.81–1.35) | 0.73 |
 Cardiovascular mortality | 29 (1.48) | 24 (1.92) | 0.79 (0.43–1.45) | 0.45 |
 Cardiovascular events | 102 (5.43) | 79 (6.62) | 0.84 (0.60–1.17) | 0.29 |
 Coronary events | 64 (3.37) | 43 (3.53) | 0.98 (0.62–1.53) | 0.91 |
 Ischaemic cerebrovascular events | 31 (1.60) | 30 (2.43) | 0.67 (0.41–1.09) | 0.11 |
TTGATGGG (N° at risk) | 788 | 1150 |  |  |
 Total mortality | 97 (7.48) | 141 (7.39) | 0.93 (0.72–1.20) | 0.58 |
 Cardiovascular mortality | 21 (1.62) | 32 (1.68) | 0.90 (0.51–1.58) | 0.72 |
 Cardiovascular events | 78 (6.25) | 103 (5.65) | 1.03 (0.76–1.39) | 0.87 |
 Coronary events | 43 (3.39) | 64 (3.46) | 0.93 (0.63–1.37) | 0.71 |
 Ischaemic cerebrovascular events | 28 (2.18) | 33 (1.75) | 1.17 (0.68–2.01) | 0.58 |
TTGATGAG (N° at risk) | 435 | 1503 |  |  |
 Total mortality | 65 (8.87) | 173 (7.00) | 1.11 (0.83–1.48) | 0.49 |
 Cardiovascular mortality | 17 (2.32) | 36 (1.46) | 1.33 (0.73–2.45) | 0.35 |
 Cardiovascular events | 44 (6.26) | 137 (5.78) | 1.00 (0.70–1.43) | 0.98 |
 Coronary events | 26 (3.66) | 81 (3.36) | 1.01 (0.63–1.63) | 0.97 |
 Ischaemic cerebrovascular events | 15 (2.07) | 46 (1.88) | 0.96 (0.54–1.70) | 0.89 |