Table 1 Baseline characteristics of participants by rs12566888 genotypes
From: PEAR1 is not a major susceptibility gene for cardiovascular disease in a Flemish population
Characteristic | T allele carriers | GG homozygotes | All |
|---|---|---|---|
N° | 363 | 1575 | 1938 |
N° with characteristics (%) | |||
 Women | 195 (53.7) | 799 (50.7) | 994 (51.3) |
 Current smoker | 101 (27.8) | 503 (31.9) | 604 (31.2) |
 Drinking alcohol | 112 (30.9) | 448 (28.4) | 560 (28.9) |
 Diabetes mellitus | 3 (0.8) | 29 (1.8) | 32 (1.7) |
 Hypertension | 84 (23.1) | 394 (25.0) | 478 (24.7) |
 Treated hypertension | 39 (10.7) | 169 (10.7) | 208 (10.7) |
 History of CVD | 8 (2.2) | 44 (2.8) | 52 (2.7) |
 Antiplatelet drugs | 70 (19.3) | 305 (19.4) | 375 (19.3) |
Mean of characteristic (±SD) | |||
 Age, years | 42.8 ± 14.1 | 43.6 ± 14.3 | 43.6 ± 14.3 |
 Body mass index, kg/m2 | 25.6 ± 4.3 | 25.7 ± 4.3 | 25.7 ± 4.3 |
 Waist-to-hip ratio | 0.84 ± 0.09 | 0.85 ± 0.09 | 0.84 ± 0.09 |
 Systolic blood pressure, mm Hg | 124.5 ± 15.2 | 125.3 ± 15.8 | 125.2 ± 15.7 |
 Diastolic blood pressure, mm Hg | 76.0 ± 9.4 | 76.2 ± 9.6 | 76.2 ± 9.5 |
 Mean arterial pressure, mm Hg | 92.2 ± 10.2 | 92.6 ± 10.6 | 92.5 ± 10.5 |
 Heart rate, beats per minute | 69.2 ± 9.5 | 69.4 ± 9.8 | 69.3 ± 9.6 |
 Total cholesterol, mmol/L | 5.47 ± 1.18 | 5.51 ± 1.15 | 5.50 ± 1.15 |
 HDL cholesterol, mmol/L | 1.39 ± 0.41 | 1.39 ± 0.39 | 1.39 ± 0.38 |
 Total-to-HDL cholesterol ratio | 4.31 ± 1.77 | 4.27 ± 1.65 | 4.27 ± 1.67 |
 Serum creatinine, μmol/L | 90.2 ± 16.6 | 91.0 ± 17.3 | 90.9 ± 17.1 |
 Plasma glucose, mmol/L | 5.12 ± 1.55 | 5.03 ± 1.32 | 5.04 ± 1.37 |