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Table 3 Genotypic class specific mean values for top SNPs from genome-wide association analyses of renal urate excretion measures

From: Genetic variation underlying renal uric acid excretion in Hispanic children: the Viva La Familia Study

SNP Trait Chr Major/Major Major/Minor Minor/Minor Direction of Changea
rs2033711 UACl 19 2.17 ± 1.79 2.79 ± 2.19 3.48 ± 2.69
rs10908521 UACl 1 2.86 ± 2.28 2.06 ± 1.66 1.86 ± 1.34
rs10423138 UACl 19 2.18 ± 1.78 2.77 ± 2.17 3.38 ± 2.68
rs9874872 UrUA/UrCr 3 0.18 ± 0.12 0.13 ± 0.10 0.11 ± 0.08
rs1353327 UrUA/UrCr 3 0.17 ± 0.11 0.11 ± 0.09 0.14 ± 0.13
rs17079585 CrCl 13 54.26 ± 32.25 22.47 ± 14.47 -
rs4889855 FEUA 17 7.22 ± 6.01 5.88 ± 5.74 4.34 ± 3.76
rs17079585 GLUA 13 3.02 ± 2.28 1.28 ± 0.77 -
  1. aDirection of associations for minor alleles of the SNPs in the genes associated with renal handling measures from GWAS; Chr chromosome, UACl uric acid clearance, UrUA/UrCr urinary uric acid to urinary creatinine ratio, CrCl creatinine clearance, FEUA fractional excretion of uric acid, GLUA glomerular load of uric acid