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Table 1 General characteristics and renal urate excretion in Hispanic children

From: Genetic variation underlying renal uric acid excretion in Hispanic children: the Viva La Familia Study

Variable Boys (N = 397) Girls (N = 371) Total (N = 768) Heritability estimates
Mean ± SD Mean ± SD Mean ± SD h2 ± SE P value
Age, years 11.88 ± 3.24 12.02 ± 3.48 11.95 ± 3.36 - -
BSA, m2 1.55 ± 0.40* 1.47 ± 0.33* 1.51 ± 0.37 - -
BSAZ 0.33 ± 0.91* 0.14 ± 0.76* 0.24 ± 0.85 - -
UrCr, mg/dL 95.37 ± 39.53 83.86 ± 32.10 89.81 ± 36.57 0.41 ± 0.10 1.9 × 10−06
CrCl, ml/min 60.59 ± 35.11* 47.41 ± 26.20* 54.22 ± 31.80 0.52 ± 0.09 2.5 × 10−10
SUA, mg/dL 5.84 ± 1.76* 4.99 ± 1.43* 5.43 ± 1.66 0.63 ± 0.09 1.4 × 10−12
UrUA, mg/dL 15.63 ± 13.19* 13.43 ± 11.41* 14.57 ± 12.40 0.70 ± 0.05 1.1 × 10−24
UACl, ml/min 2.99 ± 2.31* 2.43 ± 1.96* 2.72 ± 2.17 0.65 ± 0.06 1.7 × 10−20
UrUA/UrCr 0.17 ± 0.11* 0.16 ± 0.11* 0.16 ± 0.11 0.73 ± 0.05 1.3 × 10−25
FEUA, % 6.02 ± 5.14 6.34 ± 6.02 6.17 ± 5.58 0.74 ± 0.05 6.7 × 10−27
GLUA, mg/min/m2 3.63 ± 2.64* 2.33 ± 1.46* 3.00 ± 2.25 0.57 ± 0.09 2.2 × 10−11
EUAGF, mg/dL/m2 0.33 ± 0.30 0.30 ± 0.31 0.32 ± 0.31 0.73 ± 0.05 6.1 × 10−25
  1. *p-value is significantly different at <0.05 between boys and girls; BSA body surface area, BSAZ body surface area z-scores, UrCr urinary creatinine, SUA serum uric acid, UrUA urinary uric acid, UACl uric acid clearance, UrUA/UrCr urinary uric acid to urinary creatinine ratio, FEUA fractional excretion of uric acid, GLUA glomerular load of uric acid, EUAGF excretion of uric acid per volume of glomerular filtration. All traits for heritability analyses adjusted for age, sex, age*sex, age^2, age^2*sex, body surface area z-scores; p-value <0.05 considered statistically significant