From: Lack of direct evidence for natural selection at the candidate thrifty gene locus, PPARGC1A
obs missing (n) | NZ Caucasian | obs missing (n) | NZ Māori | obs missing (n) | CI Māori | obs missing (n) | Samoan | obs missing (n) | Tongan | |
---|---|---|---|---|---|---|---|---|---|---|
Individuals | - | 1007 | - | 322 | - | 136 | - | 223 | - | 114 |
Gout (%) | - | 64.3 | 9 | 42.5 | 1 | 52.2 | 3 | 64.6 | - | 64.0 |
Diabetes (%) | 10 | 11.5 | 11 | 42.8 | 4 | 26.5 | 6 | 14.3 | 3 | 18.4 |
Mean age (range) | - | 59.7 (18–94) | 1 | 50.9 (17–82) | - | 52.4 (18–88) | - | 44.3 (17–71) | - | 42.8 (18–79) |
Sex (% male) | 2 | 76.1 | 1 | 56.8 | - | 61.8 | 2 | 82.1 | - | 86.8 |
Mean BMI Gly/Gly (range) | 6 | 29.1 (17.8–61.6) | 1 | 32.3 (23.0–42.2) | 2 | 35.9 (33.1–40.7) | - | 37.2 (26.0–62.5) | - | 34.5 (26.3–44.2) |
Mean BMI Gly/Ser (range) | 9 | 29.3 (18.8–60.7) | 3 | 33.0 (21.3–61.7) | - | 34.5 (21.4–66.7) | 3 | 37.7 (22.2–93.4) | - | 36.5 (26.6–48.5) |
Mean BMI Ser/Ser (range) | - | 29.7 (19.3–62.9) | 3 | 34.2 (18.4–65.8) | 1 | 36.5 (23.0–80.0) | 1 | 36.7 (20.5–70.3) | 1 | 36.8 (25.8–70.6) |
Allele frequency rs8192678 Ser allele (Gout; Control) | 2 | 0.346 (0.332; 0.371) | 2 | 0.801 (0.803; 0.798) | - | 0.805 (0.782; 0.836) | - | 0.688 (0.698; 0.671) | - | 0.636 (0.651; 0.61) |
Allele frequency rs8192678 Ser allele (Diabetes; Control) | 2 | 0.346 (0.366; 0.345) | 2 | 0.801 (0.788; 0.807) | - | 0.805 (0.847; 0.786) | - | 0.688 (0.703; 0.689) | - | 0.636 (0.667; 0.622) |