Fig. 1From: Three novel mutations of STK11 gene in Chinese patients with Peutz–Jeghers syndrome a Pedigrees of family 3, 4 and 5 with PJS showed a autosomal dominant pattern and family 1, 2, and 6 were sporadic. b Sanger sequencing showed four heterozygous mutations, c.721G > C, c.752G > A, c.545 T > C, and c.645_726del. c MLPA assay showed two heterozygous gross deletions, del(exon1) and del(exon2-5)Back to article page