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Table 2 Association of SNPs with DHF

From: Association of BAK1 single nucleotide polymorphism with a risk for dengue hemorrhagic fever

SNP ID (gene) Genotype (Allele) Patients with dengue Chi-square test Logistic regression analysis
DHF DF Crude OR (95 % CI) P-value Adjusted OR (95 % CI) P-value
rs5745568 (BAK1) TT 48 47     
GT 191 187
GG 265 173
G-allele 721 (71.5 %) 533 (65.5 %) 1.32 (1.09–1.60) 0.006 1.29 (1.05–1.58) 0.016
rs6141 (THPO) TT 82 70     
CT 260 189
CC 164 148
C-allele 588 (58.1 %) 485 (59.6 %) 0.94 (0.78–1.14) 0.520 0.98 (0.80–1.19) 0.844
rs6065 (GP1BA) TT 2 0     
CT 37 42
CC 467 366
C-allele 971 (96.0 %) 774 (94.9 %) 1.29 (0.83–2.00) 0.263 1.35 (0.85–2.14) 0.203
rs739496 (SH2B3) AA 18 12     
AG 137 114
GG 350 281
A-allele 173 (17.1 %) 138 (17.0 %) 1.01 (0.79–1.29) 0.921 0.96 (0.74–1.24) 0.731
rs385893 (RCL1) TT 49 39     
CT 200 165
CC 258 205
T-allele 298 (29.4 %) 243 (29.7 %) 0.98 (0.80–1.21) 0.882 1.02 (0.83–1.25) 0.886
rs4804803 (CD209) AA 411 323     
GA 92 77
GG 4 8
  G-allele 100 (9.8 %) 93 (11.4 %) 0.85 (0.63–1.15) 0.288 0.83 (0.61–1.13) 0.242
  1. Frequencies are shown in parentheses (%). The odds ratio (OR) of rs5745568 in BAK1, rs6141 in THPO, rs6065 in GP1BA, rs739496 in SH2B3, and rs385893 in RCL1 was calculated for the allele associated with low platelet count in a previous GWAS [12]. The OR of rs4804803 in CD209 was calculated for the G allele. Genotype frequencies at SNPs examined did not deviate from those expected from the Hardy–Weinberg equilibrium in DHF and DF groups