Fig. 9

Photographs of patient 5. He is a 42-year-old male with multiple joint dislocations of the hips, knees and elbows and secondary deformities (a). Patient 5 at age 6 months (b), and 4 years (c). He showed craniofacial dysmorphism with prominent forehead, low nasal bridge, telecanthus and flattened face (a-c), cylindrical fingers and spatulate thumbs (d)