Altered miRNA expression in pulmonary sarcoidosis

BMC Medical Genetics

Table 2 Significant correlations found in the BALF cells and PB lymphocytes of sarcoidosis patients

BALF cells	Parameter	miRNA	Group/subgroup	Rho value	P-value
	AGE	miR-let7f	Parenchymal involvement	-0.44	0.001
	AGE	miR-let7f	Insidious onset	-0.34	0.01
	Ca²⁺U	miR-let7f	Acute onset	-0.45	0.04
	CD4:CD8	miR-130a	Parenchymal involvement	0.50	0.002
	FVC	miR-15b	Insidious onset	-0.33	0.02
	BALFL%	miR-192	Acute onset	-0.37	0.04
	FEV₁/FVC	miR-16	No parenchymal involvement	-0.41	0.007
	FEV₁/FVC	miR-16	Acute onset	-0.34	0.04
	Age	miR-16	Parenchymal involvement	-0.31	0.03
	FEV₁	miR-20a	Acute onset	-0.36	0.03
	Ca²⁺U	miR-128a	Acute onset	-0.49	0.03
PB lymphocytes	Age	miR-15b	Entire	-0.33	0.04
	Ca²⁺U	miRlet7f	Insidious onset	0.72	0.02
	CD4:CD8	miR-128	Entire	-0.40	0.03
	Ca²⁺S	miR-27b	No parenchymal involment	-0.59	0.02
	Ca²⁺U	miR-27b	Insidious onset	0.64	0.05

Abbreviations: BAL bronchoalveolar lavage, Ca²⁺S serum calcium concentration, Ca²⁺U calcium in 24 hrs urine collection, DLCOc lung diffusion capacity for carbon monoxide corrected for hemoglobin, FEV₁ forced expiratory volume in 1^st second of expiration, FVC forced vital capacity, PB peripheral blood; P-values of <0.05 were considered statistically significant

ISSN: 1471-2350