Fig. 1From: Molecular genetic analysis of PKHD1 by next-generation sequencing in Czech families with autosomal recessive polycystic kidney diseaseSchematic representation of fibrocystin with indicated localization of mutations detected in our study. Protein domains: green – extracellular domain, pink – transmembrane domain, violet – intracellular domain. The number of occurrence is shown for recurrent mutations. Missense mutations are shown in blue, truncating mutations in red [33]Back to article page