MTTP-297H polymorphism reduced serum cholesterol but increased risk of non-alcoholic fatty liver disease-a cross-sectional study

Table 5 Risk impact and interaction of the MTTP genotypes on serum non-HDL-C

Independent variables	Parameter estimates (B)	95 % Confidence interval		P
Independent variables	Parameter estimates (B)	Lower vs Upper bound		P
Age	0.510	0.247	0.772	<0.0001*
Sex (male vs female)	−9.122	−43.247	25.035	0.6006
BMI	1.343	0.581	2.105	0.0011*
HOMA-IR	−4.397	−6.606	−2.189	<0.0001*
Adipo-IR	4.157	2.673	5.641	<0.0001*
E98D (CC vs GG+GC)	−23.150	−83.966	37.666	0.455
I128T (CC vs TT+TC)	6.400	−12.309	25.110	0.502
N166S (GG vs AA+AG)	23.984	−34.850	82.818	0.424
Q297H (CC vs GG+GC)	−6.802	−13.386	−0.218	0.043*

Multiple linear regression analysis was applied using serum non-HDL-C as dependent variable adjusted by age, sex, BMI, HOMA-IR, Adipo-IR and MTTP genotypes based on significance in univariate analysis and regression models. (*P < 0.05 indicates significant)

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