Fig. 3
From: The importance of distinguishing between the odds ratio and the incidence rate ratio in GWAS
The estimated associations. Four scenarios are displayed: two different diseases (one rare and one common) and two different parameter settings for the likelihood of developing the disease. The probability of being diseased at age 90, i.e. the cumulative incidence rate of disease, is as follows for the four figures. a: 21.8 %, b: 2.3 %, c: 22.9 % and d: 2.6 %. Each subfigure presents the estimated association between the number of minor alleles and disease for different values of the IRR of death and the MAF. The different colours indicate different values of the IRR of death and the different line types indicate the different values of the MAF. The sloped, black solid identity line indicates no bias and the horizontal line at OR of disease = 1 indicates no association