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Table 1 Genotype and allele distributions of SNPs in MUC17 gene in Taiwanese endometriosis patients and controls

From: Genetic variations of MUC17 are associated with endometriosis development and related infertility

 

Genotype/allele

No. (%) of patients

No. (%) of controls

P-value a

Corrected P-value b

OR

95 % CI

rs4729645

TT

0 (0.0)

2 (1.0)

0.13

0.65

0.00

NA

 

CT

61 (33.0)

76 (39.8)

  

0.73

0.48-1.12

 

CC

124 (67.0)

113 (59.2)

  

1.00

 
 

T

61 (16.5)

80 (20.9)

0.12

0.6

0.71

0.47-1.09

 

C

309 (83.5)

302 (79.1)

  

1.00

 

rs10953316

AA

1 (0.5)

1 (0.5)

0.0018*

0.009*

0.77

0.05-12.65

 

AG

45 (23.8)

77 (40.5)

  

0.45

0.29-0.70

 

GG

143 (75.7)

112 (58.9)

  

1.00

 
 

A

47 (12.3)

79 (20.8)

0.0016*

0.008*

0.53

0.36-0.79

 

G

335 (87.7)

301 (79.2)

  

1.00

 

rs74974199

CC

3 (1.6)

1 (0.5)

0.24

1.2

2.86

0.29-28.61

 

CG

36 (19.4)

48 (25.4)

  

0.71

0.44-1.17

 

GG

14 7 (79.0)

140 (74.1)

  

1.00

 
 

C

42 (11.3)

50 (13.2)

0.42

2.1

0.83

0.54-1.29

 

G

330 (88.7)

328 (86.8)

  

1.00

 

rs4729655

TT

27 (14.6)

21 (11.1)

0.58

2.90

1.35

0.71-2.54

 

CT

96 (51.9)

104 (54.7)

  

0.97

0.62-1.51

 

CC

62 (33.5)

65 (34.2)

  

1.00

 
 

T

150 (40.5)

146 (38.4)

0.55

2.75

1.09

0.82-1.46

 

C

220 (59.5)

234 (61.6)

  

1.00

 

rs4729656

TT

21 (11.3)

19 (10.0)

0.90

4.5

1.17

0.59-2.34

 

AT

82 (44.1)

83 (43.7)

  

1.05

0.68-1.61

 

AA

83 (44.6)

88 (46.3)

  

1.00

 
 

T

124 (33.3)

121 (31.8)

0.66

3.3

1.07

0.79-1.45

 

A

248 (66.7)

259 (68.2)

  

1.00

 
  1. *Indicates statistical significance
  2. aP-values were calculated using χ2 test
  3. bP-values were corrected by Bonferroni correction