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Table 2 Univariate analysis of candidate SNPs selected based on literature and TagSNPs in genes involved in mental health pathways

From: Two novel genetic variants in the mineralocorticoid receptor gene associated with spontaneous preterm birth

SNP

Gene

Crude ORa

p-value

rs4128428

NR3C1

1.18

0.35

rs2070951

NR3C2

1.09

0.52

rs5522

NR3C2

1.33

0.14

rs4680

COMT

1.01

0.95

rs852978

NR3C1

0.70

0.08

rs2963155

NR3C1

0.75

0.055

rs17484063

NR3C2

0.71

0.047

rs2883929

NR3C2

0.63

0.005

rs4835136

NR3C2

0.66

0.004

rs7680420 (proxy)

NR3C2

1.60

0.017

rs173365

CRHR1

0.94

0.61

rs1912151

CRHR1

0.91

0.56

  1. Variables were analyzed using univariate logistic regression (additive model)
  2. aReferent for OR is the major allele at each site
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BMC Medical Genetics

ISSN: 1471-2350

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