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Table 3 Association test of PGR rs660149 and rs471767 in pooled subjects, Malays, Indians and Chinese ethnic groups

From: Progesterone Receptor (PGR) gene polymorphism is associated with susceptibility to preterm birth

Ethnicity/SNPs

Alleles frequencies

Adj-OR (CI)

Adj-P

 

Preterm versus term

PGR, rs660149C/G

C

G

  

Overall

0.93 vs 0.96

0.07 vs 0.04

1.8 (1.00 - 3.1)

0.041

Malays

0.91 vs 0.96

0.09 vs 0.04

2.3 (1.20 - 4.5)

0.011

Indians

0.95 vs 0.93

0.05 vs 0.07

1.3 (0.26 - 6.4)

0.758

Chinese

0.93 vs 0.09

0.07 vs 0.91

1.1 (0.20 - 6.2)

0.891

 

Preterm versus term

PGR, rs471767A/G

A

G

  

Overall

0.89 vs 0.88

0.12 vs 0.12

1.0 (0.68 – 1.6)

0.884

Malays

0.89 vs 0.96

0.11 vs 0.12

1.0 (0.53 - 1.5)

0.703

Indians

0.82 vs 0.86

0.18 vs 0.14

1.4 (0.56 – 3.7)

0.447

Chinese

0.89 vs 0.92

0.11 vs 0.08

1.1 (0.20 - 6.2)

0.891

  1. Significant p-value, P computed using multiple regression analysis
  2. P values were adjusted for previous PTB, previous miscarriage, infection and gestational diabetes
  3. Adj-P adjusted P value