From: Adjusting heterogeneous ascertainment bias for genetic association analysis with extended families
 | n proband | Statistic | N | |||||
---|---|---|---|---|---|---|---|---|
100 | 300 | 600 | 900 | 1200 | 1400 | |||
0.01 | 1 | WL | 0.052 | 0.142 | 0.369 | 0.518 | 0.682 | 0.765 |
FQLS 1 | 0.053 | 0.145 | 0.352 | 0.523 | 0.681 | 0.766 | ||
FQLS 2 | 0.056 | 0.151 | 0.389 | 0.543 | 0.702 | 0.796 | ||
2 | WL | 0.053 | 0.174 | 0.396 | 0.616 | 0.761 | 0.829 | |
FQLS 1 | 0.054 | 0.183 | 0.400 | 0.619 | 0.780 | 0.834 | ||
FQLS 2 | 0.053 | 0.202 | 0.422 | 0.658 | 0.799 | 0.859 | ||
3 | WL | 0.068 | 0.118 | 0.470 | 0.692 | 0.808 | 0.818 | |
FQLS 1 | 0.073 | 0.216 | 0.489 | 0.705 | 0.826 | 0.905 | ||
FQLS 2 | 0.067 | 0.232 | 0.498 | 0.729 | 0.826 | 0.904 | ||
4 | WL | 0.066 | 0.222 | 0.528 | 0.755 | 0.860 | 0.938 | |
FQLS 1 | 0.068 | 0.250 | 0.560 | 0.774 | 0.882 | 0.939 | ||
FQLS 2 | 0.072 | 0.244 | 0.544 | 0.766 | 0.870 | 0.935 | ||
0.001 | 1 | WL | 0.012 | 0.034 | 0.143 | 0.247 | 0.376 | 0.505 |
FQLS 1 | 0.015 | 0.046 | 0.142 | 0.245 | 0.387 | 0.496 | ||
FQLS 2 | 0.013 | 0.046 | 0.169 | 0.305 | 0.442 | 0.567 | ||
2 | WL | 0.008 | 0.060 | 0.151 | 0.342 | 0.494 | 0.612 | |
FQLS 1 | 0.014 | 0.055 | 0.163 | 0.357 | 0.512 | 0.640 | ||
FQLS 2 | 0.012 | 0.055 | 0.184 | 0.378 | 0.538 | 0.648 | ||
3 | WL | 0.005 | 0.033 | 0.223 | 0.404 | 0.579 | 0.595 | |
FQLS 1 | 0.008 | 0.076 | 0.235 | 0.432 | 0.604 | 0.717 | ||
FQLS 2 | 0.010 | 0.078 | 0.236 | 0.438 | 0.610 | 0.699 | ||
4 | WL | 0.010 | 0.079 | 0.274 | 0.484 | 0.655 | 0.763 | |
FQLS 1 | 0.008 | 0.088 | 0.296 | 0.490 | 0.677 | 0.783 | ||
FQLS 2 | 0.014 | 0.084 | 0.280 | 0.474 | 0.671 | 0.769 |