Figure 2
From: A novel large deletion of the ICR1 region including H19 and putative enhancer elements
Overview of H19/IGF2 genomic region on 11p15.5 including deletions and putative enhancer elements. Identification of candidate IGF2 enhancer regions through the integration of data of chromatin features and sequence conservation at 11p15.5. The image shows an UCSC Genome Browser screen shot including the most relevant information used to locate the putative enhancers. Two custom tracks have been added: the copy number variations track showing the extension of the 100 kb deletion described in the paper and the 137 kb deletion described by Baskin et al., 2014 (red bars); the putative enhancers of IGF2 showing four candidate regions represented by green boxes. Note that these regions correspond to evolutionary conserved intronic regions that are enriched in H3K27Ac, H3K4me1, DNase hypersensitive sites and transcription factors binding as reported by ENCODE (http://genome.ucsc.edu Chr11: 1,895,000-2,195,000; GRCh37/hg19 Feb 2009 assembly).