Figure 5
Histopathological analyses of gingiva and teeth of Family 2. (A) Histological analysis of patient gingiva revealed the presence of inflammatory infiltrate, epithelial acanthosis and gingival fibromatosis. (B) In pericoronal tissues, areas of ectopic calcifications were observed. (C) Analysis of first right molar of the patient VI-2 showed occlusal dental decay and incomplete root formation. (D) Sagittal median section of the teeth show large pulp chamber. (E) Ground sections reveal interglobular dentine except in the mantle dentine. (F) Severely affected circumpulpar dentine in increasing magnification. (G) Dentinal changes also observed in slides stained with HE after the same tooth demineralization.