Table 1 The distribution of sex, age and ethnicity amongst 771 cases and 800 controls and Odds ratios (OR) and 95% Confidence Intervals (95%CI) from nine unadjusted logistic regression models for the effect of smoking and occupational exposures on bladder cancer risk
From: Analysis of variants in DNA damage signalling genes in bladder cancer
Characteristic | Categories | Statistic | Number of Cases (%) | Number of Controls (%) | OR (95% Cl) | p-value |
|---|---|---|---|---|---|---|
| Â | Stage of bladder tumour | N (%) | Â | Â | Â | Â |
| Â | Superficial | Â | 322 (41.8) | Â | Â | Â |
| Â | Carcinoma in situ | Â | 14 (1.8) | Â | Â | Â |
| Â | T1/2 | Â | 298 (38.7) | Â | Â | Â |
| Â | T3/4 | Â | 66 (8.5) | Â | Â | Â |
| Â | Unknown | Â | 71 (9.2) | Â | Â | Â |
| Â | Grade of bladder tumour | N (%) | Â | Â | Â | Â |
| Â | G1 | Â | 87 (11.3) | Â | Â | Â |
| Â | G2 | Â | 313 (40.6) | Â | Â | Â |
| Â | G3 | Â | 325 (42.1) | Â | Â | Â |
| Â | Unknown | Â | 46 (6.0) | Â | Â | Â |
Sex | Male | N (%) | 544 (70.9) | 527 (67.3) | Â | 0.12* |
| Â | Female | Â | 223 (29.1) | 256 (32.7) | Â | Â |
Age |  | Mean (range) | 73.2 (30.1–100.7) | 73.1 (28.1–99.7) |  | 0.88** |
Ethnicity | Caucasian | N (%) | 759 (98.6) | 783 (97.9) | Â | Â |
| Â | Non-caucasian | Â | 11 (1.4) | 17 (2.1) | Â | 0.30* |
Smoking | Never | N (%) | 163 (21.3) | 254 (32.5) | 1.0 | Â |
|  | Ever |  | 603 (78.7) | 528 (67.5) | 1.78 (1.42–2.24) | <0.0001 |
Pack year |  | Median (range) | 21.0 (0–177.9) | 11.3 (0–184.0) | 1.01 (1.00–1.01) | <0.0001§ |
Rubber | Ever vs never | N (%) | 10 (1.3) | 5 (0.6) | 2.05 (0.70–6.02) | 0.18 |
Plastics | Ever vs never | N (%) | 21 (2.7) | 11 (1.4) | 1.97 (0.94–4.11) | 0.06 |
Labs | Ever vs never | N (%) | 23 (3.0) | 14 (1.8) | 1.69 (0.86–3.31) | 0.11 |
Printing | Ever vs never | N (%) | 45 (5.9) | 45 (5.8) | 1.01 (0.67–1.56) | 0.93 |
Dyes | Ever vs never | N (%) | 56 (7.3) | 27 (3.5) | 2.20 (1.37–3.52) | 0.001 |
Diesel | Ever vs never | N (%) | 88 (11.5) | 84 (10.8) | 1.07 (0.78–1.42) | 0.66 |
Number of | 0 | N (%) | 569 (74.3) | 620 (79.6) | 1.0 | Â |
occupational | 1 |  | 165 (21.5) | 139 (17.8) | 1.27 (1.06–1.51) | 0.009§ |
exposures | 2 | Â | 24 (3.1) | 14 (1.8) | Â | Â |
| Â | 3 | Â | 6 (0.8) | 5 (0.6) | Â | Â |
| Â | 4 | Â | 0 (0) | 1 (0.1) | Â | Â |
| Â | 5 | Â | 0 (0) | 0 (0) | Â | Â |
| Â | 6 | Â | 2 (0.3) | 0 (0) | Â | Â |