Table 4 Results of mitochondrial SNP association testing with ischemic stroke risk. Significant uncorrected P-values (< 0.05) are highlighted in bold. Crude and adjusted odds ratios (OR) and 95% confidence intervals (CI) are shown only for significantly associated polymorphisms.

m.709G>A

91 (18.3)

101 (19.1)

0.760

0.113

m.1719G>A

21 (4.3)

31 (5.9)

0.239

0.942

m.3010G>A

156 (31.3)

123 (23.0)

0.003

0.66 [0.50–0.87]

0.016

0.63 [0.43–0.92]

m.3348A>G

15 (3.0)

11 (2.1)

0.329

0.794

m.4580G>A

13 (2.6)

12 (2.2)

0.704

0.860

m.5999T>C

13 (2.6)

17 (3.2)

0.596

0.293

m.7028C>T

248 (50.5)

307 (59.7)

0.003

1.45 [1.13–1.87]

0.005

1.63 [1.16–2.29]

m.7805G>A

11 (2.2)

12 (2.3)

0.960

0.656

m.8251G>A

23 (4.6)

28 (5.3)

0.620

0.706

m.8701A>G

33 (6.7)

41 (7.7)

0.530

0.714

m.9055G>A

30 (6.0)

34 (6.4)

0.820

0.464

m.10398A>G

97 (19.5)

111 (20.9)

0.591

0.178

m.10873T>C

30 (6.4)

39 (7.5)

0.519

0.771

m.11719G>A

235 (47.1)

289 (54.1)

0.024

1.33 [1.04–1.69]

0.037

1.43 [1.02–1.99]

m.12308A>G

92 (18.5)

114 (21.4)

0.255

0.118

m.12705C>T

53 (11.6)

73 (14.5)

0.186

0.683

m.13368G>A

57 (11.6)

66 (12.5)

0.679

0.337

m.13617T>C

24 (4.8)

34 (6.3)

0.278

0.047

2.18 [1.01–4.70]

m.13708G>A

45 (9.0)

47 (8.9)

0.925

0.209