Figure 1
From: Mitochondrial haplogroup H1 is protective for ischemic stroke in Portuguese patients
Genomic localization of the investigated markers within the human mitochondrial DNA molecule. The genetic location of mtDNA markers genotyped in the present study is indicated in the inner circle. H and L stand for heavy and light strands, respectively, given the asymmetric distribution of G and C nucleotides, with H being the G-rich strand. The seven complex I subunits (ND1, 2, 3, 4L, 4, 5 and 6), one complex III subunit (Cyt b), three complex IV subunits (COI, COII, and COIII), two complex V subunits (ATPases 6 and 8), two ribosomal RNAs (12S and 16S rRNAs), 22 tRNAs and D-loop regions are shown. Gene products encoded by the L-strand are shown in the inner circle (one letter code) while the products of the H-strand are shown in the outer circle. Arrows indicate the locations of promoters PL and PH for the transcription and replication origin OH. Adapted from MITOMAP [2].