Table 4 Cardiovascular risk factor heritability estimates (percentage) in different studies.
From: Heritability of cardiovascular risk factors in a Brazilian population: Baependi Heart Study
Studied population | Number of Individuals Studied | Number of ascertained Families | Waist circumference | Fasting glucose | Triglycerides | HDL-c | Total Cholesterol | LDL-c | Systolic blood pressure | Diastolic blood Pressure | Body Mass Index | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Northern Manhattan Family Study [16] | Caribbean-hispanic. High cardiovascular risk individuals | 803 | 89 | 46.0 | 24.0 | 47.0 | 60 | 16.0 | 21.0 | |||
Covariates | Gender age | Gender, age, hypoglice mic drug | Gender, age, hypolipidemic drug | Gender, age, hypolipide mic drug | Gender, age, anti-hypertensive medication | Gender, age, anti-hypertensive medication | ||||||
San Antonio Family Heart Study [14] | Mexican-american individuals. High cardiovascular risk individuals | 950 | 42 | 5.8 (WHR) | 18.0 | 40.0 | 46.0 | 18.0 | 42.0 | |||
Covariates | Gender, age, age2, diabetes, diabetes duration, total dietary cholesterol ntake, menopausal status | Gender, age, age2, total protein. | Gender, age, age2, diabetes, polyunsaturated/sat rated fat intake, oral contraceptive use | Gender, total alcohol consuption, smoking status, postmenopausal estrogen use | Gender, age, age2, oral contraceptive use | Gender, age, age 2, menopausal status | Gender, age, age2, diabetes, caloric intake | Gender, age, age2, diabetes | Gender, age, age2, diabetes, diabetes duration, total dietary cholesterol intake, | |||
Community-based study of healthy families [18] | Healthy individuals, northern European ethnicity | 537 | 89 | 21.0 | 19.0 | 44.0 | 33.0 | 19.0 | 37.0 | |||
Covariates | Gender, age | Gender, age | Gender, age | Gender, age | Gender, age | Gender, age | ||||||
Chin-Shan community family study [26] | Chinese individuals. General population, mainly young individuals | 1356 | - | 17.0 | 27.2 | 26.7 | 29.9 | 32.8 | 40.1 | 32.1 | 23.2 | 21.6 |
Covariates | Not informed | |||||||||||
The Kiel obesity prevention study [16] | Northern European Caucasian with at least one overweight or obese individual in the family | 492 | 86 | 54.0 | 31.0 | 31.0 | 39.0 | 18.0 | 27.0 | |||
Covariates | Gender, age | Gender, age | Gender, age | Gender, age | Gender, age | Gender, age | ||||||
Framingham Heart Study [3] | General population | 1617 | - | 39.0 (non-fasting) | 56.0 | 62.0 | 48.0 | 51.0 | ||||
Covariates | Gender, age | Gender, age | Gender, age | Gender, age | Gender, age | |||||||
Strong Heart Family Study [20] | Native american individuals. High cardiovascular risk individuals | 950 | 32 | 29.0 | 40.0 | 50.0 | 23.0 | 34.0 | 44.0 | |||
Covariates | Gender, age, alchool consuption, estrogen use | Gender × age | Gender, age, alcohol consuption, estrogen use | Gender, age, gender × age | Gender, age, alcohol consuption, estrogen use | |||||||
Baependi Heart Study | Brazilian individuals. General population | 1666 | 81 | 40.1 | 34.5 | 28.8 | 32.0 | 29.2 | 26.3 | 25.9 | 26.2 | 51.0 |
Covariates | Gender, age, age2, gender × age | Gender, age, age2, gender × age | Gender, age, age2, gender × age | Gender, age, age2, gender × age | Gender, age, age2, gender × age | Gender, age, age2, gender × age | Gender, age, age2, gender × age | Gender, age, age2, gender × age | Gender, age, age2, gender × age |