Table 1 Genotype-phenotype correlation in the Chinese family with both RWS and JLNS and KCNQ1 mutation T322M
ID | Sex/Age | Deafness | Symptoms | QTc (s) | Genotype |
|---|---|---|---|---|---|
I:1 | M/71 | No | None | 0.420 | T322 T322 |
I:2 | F/65 | No | Chest discomfort | 0.487 | T322 M322 |
II:1 | F/42 | No | 1 syncope (trigger, exercise) | 0.430 | T322 M322 |
II:2 | M/43 | No | Palpitation, dyspnea | 0.420 0.410 0.400 | T322 M322 |
II:3 | F/39 | No | None | 0.400 | T322 T322 |
II:4 | F/36 | No | dyspnea, palpitation | 0.455 0.454 0.444 | T322 M322 |
III:1 | F/17 | Yes | 12 syncope (trigger, exercise) Atrial fibrillation | 0.520 0.608 | M322 M322 |
III:2 | M/8 | Yes | 3 syncope (trigger, exercise) | 0.512 0.627 | M322 M322 |
III:3 | M/16 | No | None | 0.397 | T322 T322 |
III:4 | M/9 | No | None | 0.447 | T322 M322 |