Table 7 Number of SNPs on different genotyping arrays within each gene region of NHLBI resequencing. Note that in all cases the entire region was not resequenced and so the first two columns are conservative and refer only to the sample of 47 people of European descent.
From: SNP selection for genes of iron metabolism in a study of genetic modifiers of hemochromatosis
Gene | NHLBI reseq total SNPs | NHLBI tagSNPs MAF≥3% r2 0.8 | Region included in basepairs | Affy 100K | Affy 500K | Affy GW5 | Affy GW6 | Illumina Humhap 300 | Illumina Humhap 550 | Illumina Human 1M |
|---|---|---|---|---|---|---|---|---|---|---|
ACO1 | 276 | 26 | 69937 | 1 | 11 | 12 | 24 | 14 | 26 | 41 |
CYBRD1 | 139 | 16 | 39535 | 0 | 3 | 3 | 8 | 7 | 12 | 19 |
FLVCR | 185 | 17 | 40442 | 4 | 6 | 6 | 15 | 11 | 12 | 18 |
HAMP | 43 | 4 | 6314 | 0 | 2 | 2 | 3 | 1 | 1 | 4 |
HCP1 | 65 | 3 | 11169 | 0 | 0 | 0 | 0 | 1 | 2 | 7 |
HEPH | 177 | 13 | 101478 | 1 | 11 | 10 | 32 | 5 | 7 | 21 |
HFE2 | 38 | 5 | 7437 | 0 | 1 | 1 | 2 | 0 | 1 | 5 |
IREB2 | 241 | 11 | 64450 | 1 | 15 | 11 | 21 | 3 | 7 | 24 |
PGRMC1 | 33 | 5 | 12051 | 0 | 0 | 0 | 1 | 1 | 1 | 7 |
PGRMC2 | 55 | 2 | 21640 | 0 | 1 | 1 | 4 | 2 | 3 | 9 |
TF | 158 | 20 | 33189 | 0 | 23 | 18 | 37 | 8 | 11 | 23 |
TFR2 | 56 | 4 | 21649 | 0 | 0 | 0 | 1 | 3 | 3 | 13 |
TFRC | 314 | 36 | 36402 | 2 | 4 | 4 | 10 | 7 | 8 | 14 |