Aryl hydrocarbon receptor nuclear translocator (ARNT) gene as a positional and functional candidate for type 2 diabetes and prediabetic intermediate traits: Mutation detection, case-control studies, and gene expression analysis

Table 3 Raw counts of cases and controls by genotype for ARNT region SNPs in Caucasians and African Americans

Position	RS number	Population	Variant	Control			Type 2 Diabetes
				DD	Dd	dd	DD	Dd	dd
-992	rs7517566	AA	C/T	132	53	6	276	86	8
7377	rs11204735	UT AA	G/A A/G	60 129	81 61	41 2	60 260	96 102	34 10
32158	rs2134688	UT AR	T/C T/C	158 167	17 24	7 2	157 176	33 37	0 3
34242	rs10305679	AA	T/C	116	64	10	243	112	16
38039	rs10305685	AA	A/G	122	63	7	264	95	11
39928	rs10305695	UT	G/A	169	11	2	179	12	0
46017	rs10305710	UT	C/T	158	19	1	171	11	2
47578	rs3738483	AA	C/T	84	81	26	175	152	43
48389	rs10305714	UT AA	T/C T/C	82 114	74 65	26 12	86 201	82 142	20 27
49289	rs1889740	UT AA	C/T C/T	78 58	76 87	28 45	83 102	83 179	24 88
50312	rs10305718	AA	G/C	130	56	5	247	108	16
53679	rs10305724	UT	C/T	170	9	3	168	23	0
56428	rs11589458	AA	T/C	128	56	9	230	119	22
65586	rs10305751	AA	C/T	142	49	1	289	74	9
66247	rs10847	UT	C/T	88	74	21	102	68	19
68462	rs4379678	UT	T/C	158	17	7	157	33	0

Position is shown relative to ATG start site. Variants are shown for the major/minor allele, as genotyped. Populations are as described in Table 1: UT, Utah Caucasian; AR, Arkansas Caucasian; AA, African-American. The total number of samples genoytped varies due to genotyping success rates, and may differ from the totals in Table 1.

ISSN: 1471-2350