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Table 2 Histamine receptor polymorphisms in patients with PD and healthy controls.

From: Genetic variability of histamine receptors in patients with Parkinson's disease

GENOTYPE PATIENTS WITH PD NO (%) HEALTHY SUBJECTS NO (%) INTERGROUP COMPARISON VALUES ODDS RATIO (95% C.I) [CHI-SQUARE; P VALUE]
H1 Leu/Leu 193 (99.0) 231 (100) 0.46a (0.46–1.34) [2.38; 0.123]
H1 Leu/Ser 2 (1.0) 0 --- 2.20 a (0.75–2.20) [2.38; 0.123]
H1 Ser/Ser 0 --- 0 --- ---
H2 -1018 G/G 183 (93.9) 208 (90.0) 1.69 (0.83–3.44) [2.03; 0.154]
H2 -1018 G/A 10 (5.1) 23 (10.0) 0.49 (0.23–1.04) [3.44; 0.063]
H2 -1018 A/A 2 (1.0) 0 --- 2.20 a (0.75–2.20) [2.38; 0.123]
Total 195 231  
HRH1 Allele frequency    
H1 Leu 388 (99.5) 462 (100) 0.46 a (0.46–1.34) [2.37; 0.124]
H1 Ser 2 (0.5) 0 (0) 2.19 a (0.74–2.19) [2.37; 0.124]
Total 390 462  
HRH2 Allele frequency    
H2 -1018 G 376 (96.4) 439 (95.0) 1.41 (0.72–2.74) [0.98; 0.322]
H2 -1018 A 14 (0.6) 23 (5.0) 0.71 (0.37–1.39) [0.98; 0.322]
Total 390 462  
  1. Crude Odds ratios are shown. (a) In cases where comparison values included zero the relative risk ratio is shown instead of the Odds Ratio.