Table 2 Histamine receptor polymorphisms in patients with PD and healthy controls.
From: Genetic variability of histamine receptors in patients with Parkinson's disease
GENOTYPE | PATIENTS WITH PD NO (%) | HEALTHY SUBJECTS NO (%) | INTERGROUP COMPARISON VALUES ODDS RATIO (95% C.I) [CHI-SQUARE; P VALUE] |
|---|---|---|---|
H1 Leu/Leu | 193 (99.0) | 231 (100) | 0.46a (0.46–1.34) [2.38; 0.123] |
H1 Leu/Ser | 2 (1.0) | 0 --- | 2.20 a (0.75–2.20) [2.38; 0.123] |
H1 Ser/Ser | 0 --- | 0 --- | --- |
H2 -1018 G/G | 183 (93.9) | 208 (90.0) | 1.69 (0.83–3.44) [2.03; 0.154] |
H2 -1018 G/A | 10 (5.1) | 23 (10.0) | 0.49 (0.23–1.04) [3.44; 0.063] |
H2 -1018 A/A | 2 (1.0) | 0 --- | 2.20 a (0.75–2.20) [2.38; 0.123] |
Total | 195 | 231 | |
HRH1 Allele frequency | |||
H1 Leu | 388 (99.5) | 462 (100) | 0.46 a (0.46–1.34) [2.37; 0.124] |
H1 Ser | 2 (0.5) | 0 (0) | 2.19 a (0.74–2.19) [2.37; 0.124] |
Total | 390 | 462 | |
HRH2 Allele frequency | |||
H2 -1018 G | 376 (96.4) | 439 (95.0) | 1.41 (0.72–2.74) [0.98; 0.322] |
H2 -1018 A | 14 (0.6) | 23 (5.0) | 0.71 (0.37–1.39) [0.98; 0.322] |
Total | 390 | 462 |