Table 3 Genotype frequency distribution among the two follow-up groups (events vs non events).
From: Role of TGF-β1 haplotypes in the occurrence of myocardial infarction in young Italian patients
Polymorphism | Genotype | Events (%) | No events (%) | P value | Crude ORs (95%CI) | P value | Adjusted ORs (95%CI) | P value |
|---|---|---|---|---|---|---|---|---|
G-800A | GG | 50 (82.0%) | 97 (89.8%) | 1 | 1 | |||
AG | 11 (18.0%) | 10 (9.3%) | a0.196 | 2.134 (0.849–5.365) | 0.107 | 2.145 (0.850–5.412) | 0.106 | |
AA | 0 (0%) | 1 (0.9%) | 0.000 (0.000) | 1 | 0.000 (0.000) | 1 | ||
C-509T | CC | 19 (31.1%) | 40 (37.0%) | 1 | 1 | |||
CT | 30 (49.2%) | 39 (36.1%) | a0.241 | 1.619 (0.785–3.342) | 0.192 | 1.839 (0.801–4.226) | 0.151 | |
TT | 12 (19.7%) | 29 (26.9%) | 0.871 (0.366–2.072) | 0.755 | 1.024 (0.425–2.470) | 0.957 | ||
Leu10Pro | TT | 14 (23.0%) | 32 (29.4%) | 1 | 1 | |||
CT | 26 (42.6%) | 45 (43.4%) | a0.588 | 1.321 (0.598–2.916) | 0.491 | 1.434 (0.639–3.215) | 0.382 | |
CC | 21 (34.4%) | 31 (27.2%) | 1.548 (0.670–3.577) | 0.306 | 1.711 (0.728–4.022) | 0.218 |