Table 2 Distribution of the GABRQ gene exon 9 variation (P437I) in migraineurs and controls of original sample (MO migraine without aura, MA migraine with aura).
From: Investigation of Gamma-aminobutyric acid (GABA) A receptors genes and migraine susceptibility
| Â | N | Alleles | Â | Â | Genotypes | Â |
|---|---|---|---|---|---|---|
| Â | (alleles) | A | T | AA | AT | TT |
GABRQ SNP | rs 3810651 | Â | Â | Â | Â | Â |
Migraine | 350 | 210 (60%) | 140 (40%) | 82 (40%) | 74 (37%) | 46 (23%) |
Male | 54 | 28 (51.8%) | 26 (48.2%) | Â | Â | Â |
Female | 296 | 182 (61.5%) | 114 (38.5%) | 54 (36%) | 74 (50%) | 20 (14%) |
MA | 208 | 131 (63%) | 77 (37%) | 54 (45%) | 43 (35%) | 24 (20%) |
MO | 140 | 77 (55%) | 63 (55%) | 27 (34%) | 31 (39%) | 22 (27%) |
Control | 367 | 226 (61%) | 141 (39%) | 94 (44%) | 72 (34%) | 47 (22%) |
Male | 59 | 33 (55.9%) | 26 (44.1%) | Â | Â | Â |
Female | 309 | 194 (62.8%) | 115 (37.2%) | 61 (40%) | 73 (47%) | 21 (13%) |
Total case vs control | Â | X2 = 0.19 | P = 0.664 | Â | X2 = 0.57 | P = 0.753 |
Subtype MA vs cont: | Â | X2 = 0.11 | P = 0.739 | Â | X2 = 0.25 | P = 0.881 |
Subtype MO vs cont | Â | X2 = 1.82 | P = 0.176 | Â | X2 = 2.65 | P = 0.265 |