Table 1 Overview of the results for the exon 45–55 multiexon skipping experiments in control cells
From: Assessment of the feasibility of exon 45–55 multiexon skipping for duchenne muscular dystrophy
Used AONs | Exon 45–55 skip | NT | Other skips | NT |
|---|---|---|---|---|
Exon 45 & 55 (mix) | 1/6 | 0/6 | Exon 45–52 skip (1×) | Exon 45–54 skip (1×) |
0/6 | 1/6 | Exon 45–53 skip (1×) | ||
Exon 45 & 55 (linked) | 1/6 | 1/6 | Exon 45–51 & 54–55 skip (1×) | Exon 45–51 skip (1×) |
5/5 | 5/5 | Exon 48–55 skip (1×) | ||
Exon 45, 46, 47, 48, 49, 50, 51, 52, 53, 54 & 55 | 1/6 | 1/6 | Exon 45–47 & 49–55 skip (1×) | Exon 45–51 skip (1×) |
5/5 | 5/5 | Exon 48–55 skip (1×) |