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Table 2 Major QTL findings per chromosome, LOD > 1.7 in whites

From: QTLs of factors of the metabolic syndrome and echocardiographic phenotypes: the hypertension genetic epidemiology network study

No

Rotation

Excluding DM

Chromosome

Sex-averaged distance in cM, peak and (surrounding markers)

Marker name

Dname

LOD* Score

Factor Domain

1

NO

NO

3

114.32 (112.42)

GATA128C02

D3S4529

2.71

LV WALL THICKNESS

2

  

16

113.46 (113.52)

AFM031XA5

D16S402

1.79

LV WALL THICKNESS

3

  

20

4.13 (2.13)

AFM077XD3

D20S103

1.82

BP-LV WALL THICKNESS

4

NO

YES

3

201.32 (201.14)

AFM059XA9

D3S1262

1.98

BP-LV GEOMETRY

5

  

3

224.88

AFM254VE1

D3S1311

2.79

BP-LV WALL THICKNESS

6

  

12

98.42 (95.03)

GATA63D12

D12S1064

2.32

BMI-INS

7

  

15

78.30 (82.84)

ATA28G05

D15S655

1.90

LV WALL THICKNESS

8

  

16

113.46 (113.52)

AFM031XA5

D16S402

2.61

LV WALL THICKNESS

9

  

20

2.13

AFM077XD3

D20S103

2.61

BP-LV WALL THICKNESS

10

VAR†

NO

3

5.32 (5.54)

GATA22G12

D3S2387

2.01

BMI-INS

11

  

3

114.32 (112.42)

GATA128C02

D3S4529

2.18

LV WALL THICKNESS

12

  

11

17.11 (8.9)

ATA33B03

D11S2362

1.81

BMI-INS

13

  

12

47.42 (48.7)

ATA27A06

D12S1042

1.99

LV GEOMETRY

14

  

16

113.46 (113.52)

AFM031XA5

D16S402

1.72

LV WALL THICKNESS

15

  

21

19.99 (24.73)

GATA129D11

D21S2052

1.81

LV WALL THICKNESS

16

VAR

YES

3

218.32 (215.84)

ATA22E01

D3S2418

2.26

LV GEOMETRY

17

  

11

28.11 (33.02)

ATA34E08

UNKNOWN

1.72

BMI-INS

18

  

12

87.42 (95.03)

GATA63D12

D12S1064

2.00

BMI-INS

19

  

14

107.46 (105.53)

GGAA21G11

D14S617

1.87

BP

20

  

16

113.46 (113.52)

AFM031XA5

D16S402

2.81

LV WALL THICKNESS

  1. * Logarithm of odds; †Varimax rotation