Genome-wide association of sleep and circadian phenotypes

BMC Medical Genetics

Table 1 Sleep phenotypic characteristics of Family Plate Set subjects

Phenotype	N	Offspring Exam cycle	Unadjusted Mean (SD)	Adjustment variables	Heritability (SE)	Webpost name*
Epworth Sleepiness Scale score	721	6	6.4 (3.8)	age, sex, BMI	0.29 (0.09)	essresid1
Usual bedtime, (hr:min)	738	6	10:50 PM (1:06)	age, sex, BMI	0.22 (0.08)	bedtimeresid
Usual sleep duration, hrs	736	6	7.28 (1.06)	age, sex, BMI	0.17 (0.08)	sleepdurresid

*The age-, sex- and BMI-adjusted residual apnea-hypopnea index (rdiresid) is also posted in the on-line repository, although it is not discussed in this manuscript. Also posted in the on-line repository but not included in this manuscript are the unadjusted Epworth Sleepiness Scale score (ess), usual bedtime (bedtime), and usual sleep duration (sleepdur), as well as Epworth Sleepiness Scale score additionally adjusted for usual sleep duration (essresid2) and for both usual sleep duration and the presence of self-reported sleep-disordered breathing symptoms of snoring three or more nights per week or any witnessed nocturnal apneas (essresid3).

ISSN: 1471-2350