The Framingham Heart Study 100K SNP genome-wide association study resource: overview of 17 phenotype working group reports

Table 2 Description of Framingham Heart Study Subjects in 100K Genome-Wide Scan.

	Original Cohort Men	Original Cohort Women	Offspring Cohort Men	Offspring Cohort Women
	N = 90	N = 168	N = 527	N = 560
Age, years	35 ± 4	35 ± 4	31 ± 10	32 ± 10
(Limits)	(30–46)	(29–48)	(11–62)	(5–59)
Body Mass Index, kg/m²	25.7 ± 3.2	23.9 ± 3.6	26.0 ± 3.9	23.6 ± 4.3
Obese (BMI 30 ≥kg/m²), %	7.8	6.0	13.3	8.2
Systolic Blood Pressure, mm Hg	129 ± 13	120 ± 12	124 ± 14	115 ± 14
Diastolic Blood Pressure, mm Hg	81 ± 9	76 ± 8	81 ± 10	75 ± 10
Antihypertensive Medication, %	0	0	1.7	1.4
Hypertension, %	22.2	8.9	15.0	6.8
Current Smoking, %	61.1	42.3	40.0	41.3
Blood Glucose, mg/dL	78 ± 13	78 ± 11	102 ± 10	97 ± 9
Prevalent Diabetes, %	0	0	0.6	0.4
Total Cholesterol, mg/dL	220 ± 44	194 ± 37	192 ± 37	185 ± 36
HDL Cholesterol, mg/dL	N/A	N/A	44.9 ± 11.0	56.4 ± 13.9
Lipid Lowering Medication, %	0	0	0.2	0.5
Hemoglobin, g/dL	14.3 ± 1.2	12.3 ± 1.1	15.5 ± 1.0	13.5 ± 1.0
Forced Vital Capacity, dL	40 ± 7	28 ± 6	45 ± 8	32 ± 5
Prevalent CVD, %	0	0	5.5	2.6

Abbreviations: BMI = body mass index; HDL = high density lipoprotein; CVD = cardiovascular disease.

Baseline Data at Exam 1 for Original (1948–1951) and Offspring (1971–1975) Cohorts

ISSN: 1471-2350