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Table 1 Baseline characteristics of low HDL-C and control subjects

From: Sphingomyelin phosphodiesterase-1 (SMPD1) coding variants do not contribute to low levels of high-density lipoprotein cholesterol

  Control subjects (n = 230) Low HDL-C subjects (n = 118) t test p*
Age (y) 50 ± 9 50 ± 10 0.93
Gender (M/F) 150/80 85/33 0.20
BMI (kg/m2) 26.3 ± 4.5 28.1 ± 4.9 0.001
DM (%) 10.4 21.2 0.01
HTN (%) 20.4 45.8 <0.001
CAD (%) 49.8 72.3 <0.001
FH of CAD (%) 61.3 72.6 0.04
TG (mmol/L) 1.63 ± 0.89 3.95 ± 3.35 <0.001
T Chol (mmol/L) 5.73 ± 1.41 5.98 ± 2.20 0.26
HDL-C (mmol/L) 1.35 ± 0.33 0.67 ± 0.13 <0.001
LDL-C (mmol/L) 3.70 ± 1.33 3.50 ± 1.61 0.27
  1. BMI, body mass index; DM, diabetes mellitus; HTN, hypertension; CAD, coronary artery disease; FH, familial history; TG, plasma triglycerides; T Chol, total plasma cholesterol; HDL-C, plasma high-density lipoprotein cholesterol; LDL-C, plasma low-density cholesterol.
  2. * significant p-value bolded.