No evidence for association between taugene haplotypic variants and susceptibility to Creutzfeldt-Jakob disease

BMC Medical Genetics

Table 4 Haplotype analysis of the association between MAPT and Creutzfeldt-Jakob disease

Haplotype	Alleles						Frequency		P-value	Frequency		P-value
	rs242559	rs242557	rs3785883	rs2471738	H1/H2	rs7521	Controls	sCJD		UK sCJD	UK vCJD
H1e	A	G	G	C	G	A	0.25	0.26	ref	0.24	0.2	0.51
H2a	C	G	G	C	A	G	0.23	0.22	0.64	0.28	0.31	ref
H1c	A	A	G	T	G	G	0.12	0.15	0.46	0.16	0.1	0.4
H1d	A	A	G	C	G	A	0.13	0.1	0.08	0.07	0.16	0.18
H1f	A	G	A	C	G	G	0.05	0.05	0.88	0.08	0.02	0.04
H1g	A	A	G	C	G	G	0.05	0.05	0.91	_	_	_
H1h	A	G	A	C	G	A	0.04	0.04	0.64	_	_	_
H1i	A	A	A	C	G	A	0.03	0.03	0.68	_	_	_
H1j	A	A	A	T	G	G	0.03	0.02	0.45	0.01	0.07	0.01
H1b	A	G	G	C	G	G	0.02	0.02	0.55	_	_	_

ISSN: 1471-2350