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Table 2 Gender and age distribution of the PTPN22 C1858T polymorphism in Spanish T1D patients

From: Susceptibility to type 1 diabetes conferred by the PTPN22C1858T polymorphism in the Spanish population

  Genotypes (%) T1D vs. Controls (carrier of T vs CC)
Subjects CC CT TT OR CI (95%) p
Female T1D ≤ 15 (n = 70) 49 (70.0) 19 (27.1) 2 (2.9) 2.92 (1.59–5.33) 0.0001
Male T1D ≤ 15 (n = 71) 61 (85.9) 10 (14.1) 0 1.12 (0.51–2.37) 0.76
Female T1D > 15 (n = 70) 56 (80.0) 12 (17.1) 2 (2.9) 1.70 (0.85–3.34) 0.10
Male T1D > 15 (n = 70) 56 (80.0) 13 (18.6) 1 (1.4) 1.70 (0.85–3.34) 0.10
Controls 483 (87.2) 68 (12.3) 3 (0.5)   
  1. Female T1D ≤ 15 vs. Male T1D ≤ 15:
  2. (TT+CT) vs. CC; OR (95%) = 2.61 (1.05–6.62); p = 0.022